Amy Schumer Reveals Internet Trolls Helped Her Discover She Had Cushing’s Syndrome

Amy Schumer credits Internet trolls for inadvertently helping her discover she had Cushing syndrome. The Kinda Pregnant star shared that comments about her swollen appearance prompted doctors to take notice, ultimately leading to her diagnosis.

“A year ago, the Internet really came for me,” Amy Schumer, 43, shared on the Jan. 22 episode of the Call Her Daddy podcast with Alex Cooper, revealing how commenters criticized her suddenly swollen face.

Initially, Schumer dismissed the remarks. “I was like, ‘Okay, everybody, like, relax,’ ” she said. But when physicians began commenting with potential diagnoses based solely on her appearance, she started to pay attention. “Doctors were chiming in in the comments and they were, like, ‘No, no … something's really up. Your face looks so crazy.’ ”

The Trainwreck star revealed that doctors suspected she might have Cushing syndrome, a condition the Mayo Clinic explains occurs when the stress hormone cortisol remains in the body for too long. It can result from prolonged steroid use and is associated with symptoms such as weight gain, acne, and a distinctive facial swelling known as “moon face.”

“At first, I was like, ‘Back off,’ ” Schumer admitted, but later reconsidered. “Wait, I have been getting steroid injections for my scars,” she said, referring to treatment following her breast reduction and Cesarean section. (Schumer and her husband, Chris Fischer, welcomed their son, Gene, now 5, in 2019.)

“So I was getting these steroid injections, and it gave me this thing called Cushing syndrome — which I wouldn't have known if the internet hadn't come for me so hard,” Schumer explained. She first disclosed her Cushing syndrome diagnosis in February 2024.

Last year, Amy Schumer's appearances on The Tonight Show and Good Morning America to promote the new season of Life & Beth drew attention, with viewers commenting on her face appearing "puffier." Fans speculated about a condition known as "moon face," which can result from various causes.

In a viral tweet, someone posed a question to doctors, asking, "Serious question, what happened to Amy’s face? Is it normally this size?" Many experts joined the conversation to share their thoughts.

"Honestly, it looks like what is referred to as 'moon face,'" one replied. Another tweeted, "That’s a steroid to treat illness. Let’s be kind and mind our own business." A third commenter added, "Looks like prednisone. I’ve had moon face from prednisone. It’s pretty awful to experience."

In 2021, Amy Schumer opened up about her diagnosis in an Instagram video, sharing that she underwent a hysterectomy and an appendectomy to treat her condition. She described the surgeries as life-changing, saying they made her feel like a “new person.”

Previously, Schumer had spoken about enduring “quite intense pain,” referring to endometriosis as the “loneliness disease.” Reflecting on her journey, she shared, “Sometimes I feel damn confident and good, and sometimes I want to put a bag over my head.” Despite these struggles, she hopes fans will focus on her accomplishments.

Meanwhile, a 60-year-old woman has issued a warning about the risks of beauty procedures after receiving botched fillers from a fake doctor. Her bravery and determination have earned widespread admiration, and her openness has sparked vital conversations about the importance of making informed decisions when considering cosmetic alterations.